Homemade Stuffing Meatloaf for Cozy Weeknight Dinners

This Homemade Stuffing Meatloaf is a perfect blend of savory ground beef and aromatic stuffing, creating a hearty, flavorful dish that's perfect for busy weeknights.

Print Recipe Pin Recipe

Prep Time 15

Cook Time 50

Resting Time 10

Total Time 1 15

Servings: 6 slices

Course: Dinner

Cuisine: American

Calories: 320

Ingredients Equipment Method Nutrition Notes

Ingredients

For the Meatloaf

1 lb Ground Beef (80/20 blend) Provides structure and flavor; can substitute with ground turkey or pork.
1 box Stuffing Mix Secret for moisture and flavor; try homemade breadcrumbs if desired.
1/2 cup Ketchup Adds sweet and tangy glaze; BBQ sauce can be a twist.
1/2 cup Water Aids in binding; broths can enhance flavor.
2 Eggs (room temperature) Essential for binding; use flax eggs as a vegan alternative.

For Topping (Optional)

Additional Ketchup Enhances flavor, spreads over the top of the meatloaf.

Equipment

mixing bowl
Loaf Pan
Oven

Method

Step‑by‑Step Instructions

Preheat your oven to 375°F (190°C). Gather all ingredients, mixing bowl, and loaf pan or baking sheet.
In a large mixing bowl, combine ground beef, stuffing mix, eggs, ketchup, and water. Mix until just combined.
Transfer mixture to greased loaf pan or shape into a loaf on baking sheet, about 2 inches high.
Spread a layer of ketchup on top of the meatloaf for extra flavor.
Bake for 45-50 minutes until internal temperature reaches 165°F (74°C) and exterior is browned.
Let the meatloaf rest for 10 minutes before slicing and serving.

Nutrition

Serving: 1sliceCalories: 320kcalCarbohydrates: 22gProtein: 24gFat: 15gSaturated Fat: 5gPolyunsaturated Fat: 1gMonounsaturated Fat: 8gCholesterol: 100mgSodium: 600mgPotassium: 400mgFiber: 1gSugar: 4gVitamin A: 2IUVitamin C: 4mgCalcium: 2mgIron: 10mg

Notes

Perfect for repurposing leftover stuffing; customizable with different proteins or stuffing flavors.

Tried this recipe?

Let us know how it was!