Preheat your grill or skillet over medium-high heat to about 400°F.

In a large mixing bowl, combine the ground beef, garlic powder, onion powder, smoked paprika, salt, and pepper until just combined.

Divide the mixture into four equal portions and shape into patties, making a slight indentation in the center.

Cook the patties on the grill for 4-5 minutes, then flip, add cheese, and cook for another 3-4 minutes until cheese melts.

Toast the hamburger buns on the grill for about 1-2 minutes until golden brown.

Assemble the burger by spreading barbecue sauce on the bottom bun, layering with patty, bacon, onion strings, lettuce, tomato, pickles, and topping.

Serve the assembled Cowboy Burgers immediately.